Tobacco Science & Technology, 2012, 2, p. 43-46., ISSN.1002-0861
Determination of NNN and its metabolites in rabbit blood with HPLC-MS/MS
(1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, P.R. China; (2) Quality Supervision & Test Station of Hainan Tobacco Corporation, Haikou 571100, P.R. China; (3) Quality Supervision & Test Station of Zhejiang Tobacco Corporation, Hangzhou 310001, P.R. China
In order to accurately determine N-nitroso nornicotine (NNN) and its metabolites in rabbit blood, a high-performance liquid chromatography/tandem mass spectrometry method was established by optimizing chromatographic conditions and mass spectrometric ...