Synthesis of vitamin E succinate and its conversion to vitamin E in cigarette smoke
It was reported that the consumption of vitamin E of a smoker is higher than that of a non-smoker by about 30%. In order to supplement vitamin E and improve cigarette taste, vitamin E succinate was synthesized from vitamin E and succinic anhydride by using DCC (dicyclohexylcarbodiimide) as catalyzer, its purity was measured as 98% by HPLC and its structure was identified by 1H NMR, 13C NMR and MS. The synthesized Vitamin E succinate was added to Virginia type cigarette, and the cigarette smoke analysis results showed that vitamin E succinate could increase the content of vitamin E in cigarette smoke, which released vitamin E by pyrolytic reaction during smoking. The results of panel test also showed that vitamin E succinate could decrease the irritation and harshness of cigarette, improve the taste and quality of cigarette, and increase the content of vitamin E in the body of smokers.