Search Results

24 results

  1. CORESTA Meeting, Smoke Science/Product Technology, Jeju, 2007, SSPT 45

    Gene expression analysis of human lung cells treated with cigarette smoke

    ACHARD S.; VERRON T.; SEVESTRE O.; DUMERY B.
    Altadis - Imperial Tobacco Group, Research Center, Fleury les Aubrais, France
    Gene expression profiling is considered as a promising tool that may identify more sensitive, mechanism-based biomarkers. Such an experimental approach should provide a better understanding of the impact of chemical compounds on the intracellular ...
  2. CORESTA Congress, Paris, 2006, SS 01

    How representative of the human smoking behaviour would be the new alternative smoking regimes? A first attempt of assessment

    MARCHAND V.; TESSIER C.; DUMERY B.
    Altadis Research Centre, Fleury-les-Aubrais, France
    The ISO or FTC smoking conditions (35 mL- 2 s puffs, 1 puff per minute) have been more and more criticized during the last decade, especially because they would not reflect the human smoking behaviour. Their main objective was not to predict the exact ...
  3. CORESTA Congress, Kyoto, 2004, PT 08

    Hoffmann analytes: Influence of cigarette paper and filter ventilation

    LOUREAU J.M.; BIESSE J.P.; CLARISSE G.; VIDAL B.; DUMERY B.; LE MOIGNE C.; LE BEC L.; LE BOURVELLEC G.
    Papeteries de Mauduit, Quimperlé, France; Altadis, Les Aubrais, France
    Having a tool that can predict the Hoffmann analytes has become necessary, not only because of regulations, but also as a reference for the chemical composition of smoke for the Potential Reduced Exposure Products (PREPs). The work presented in this paper ...
  4. CORESTA Congress, Kyoto, 2004, SS 14

    Prediction of a biological variable (Ames test on TPM) and of a chemical variable (TSNAs in smoke) according to the tobacco's chemical and physical characteristics

    BOUZIGE M.; VIDAL B.; BIESSE J.P.; JOUSSERAND C.; MARCHAND V.; DUMERY B.
    Altadis Research Centre, Fleury-les-Aubrais, France
    Chemical analyses of special analytes (e.g. TSNAs) or biological tests on the smoke are rather sophisticated and time consuming technologies. Giving estimates based on fast analyses would enable the blenders to have a tool allowing them to reduce tobacco ...
  5. CORESTA Congress, Kyoto, 2004, SSPT 02

    Near-infrared spectroscopy and pattern recognition as screening methods for classification of commercial tobacco blends

    FIGUERES G.; ANDRIEU E.; BIESSE J.P.; VIDAL B.; DUMERY B.
    Altadis Research Centre, Fleury-les-Aubrais, France
    Group classification of tobacco blends is commonly performed using several different types of compositional data including tobacco compounds, additive or process components. But all of these wet chemistry methods are relatively time-consuming. A need ...