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  1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 15

    Crystal structure of nicotine gentisate and its permeability in pig buccal mucosa

    YANG Ji; MIAO Mingming; CHEN Yongkuan; LIU Zhihua; ZHAO Yang; WU Yiqin; LIU Chunbo; YANG Liu; ZHAO Hui; SHEN Qinpeng; DUAN Yuanxing; GONG Xiaowei
    R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    Nicotine compound salt has been widely concerned recently with the continuous expansion of the e-cigarette market. Synthetic nicotine organic acid salt or nicotine complex, instead of monomeric nicotine, is used in the formulation of the next...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 52

    Investigation of nicotine release behaviour of tobacco chewing gum in oral cavity by a novel simulated oral dissolution device

    YANG Ji; YANG Liu; ZHAO Wei; TANG Jianguo; ZHOU Kun; ZHU Baokun; DUAN Yuanxing; ZHAO Yang; TIAN Yongfeng; CHEN Yongkuan; MIAO Mingming
    Yunnan Industrial Co., Ltd of CNTC, Research & Development Center, Kunming, P.R. China
    For studying the nicotine release behaviours of smokeless tobacco products in the oral cavity, a controllable and reliable method was established and a novel simulated oral dissolution device was designed. Taking the in vivo nicotine dissolution...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 11

    Investigation of gene expression profile of cells after e-cigarette and cigarette smoke exposure

    TIAN Yongfeng; DUAN Yuanxing; ZHAO Wei; YANG Ji; ZHAO Yang; ZHU Donglai; ZHANG Xia; GONG Xiaowei; HONG Liu; MIAO Mingming; YANG Liu; CHEN Yongkuan
    China Tobacco Yunnan Industrial Co., Ltd of CNTC, Technical and Research Center, Yunnan, P.R. China
    To evaluate the cellular damage caused by e-cigarettes (e-cigs) and combustible cigarettes with respect to inflammatory expression, comparative analysis between two types of e-cigs and three types of combustible cigarettes were conducted. The aerosol...