Search Results

21 results

  1. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 012

    Equivalence testing in demonstrating substantial equivalence for new tobacco products

    FROST-PINEDA K.(1); CAMPBELL L.R.(1); POLSTER M.(2); CURTIN G.M.(1)
    (1) RAI Services Company, Winston Salem, NC, USA; (2) Naxion, Philadelphia, PA, USA
    Under Section 905j of the Tobacco Control Act, manufacturers must submit reports to the FDA to demonstrate that a new tobacco product is substantially equivalent (SE) to a “predicate product.” Demonstrating equivalence with traditional statistical ...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 036

    Trends in US smokers' perceptions of the relative risks of non-combustible tobacco products versus cigarettes

    CURTIN G.M.(1); SHIFFMAN S.(2); ROHAY J.(2); PYPE S.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) PinneyAssociates, Inc., Pittsburgh, PA, USA
    Smokers can benefit from switching to less harmful tobacco products, which requires knowledge of relative product risk. However, publicly shared information often emphasizes absolute rather than relative risks. To understand smokers’ perceptions of ...
  3. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 037 (also presented at CORESTA 2018)

    Multi-dimensional tipping point analyses: assessing simultaneous shifts in tobacco use patterns from a higher to a lower risk product

    CURTIN G.M.(1); BACHAND A.(2); SULSKY S.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Ramboll US Corporation, Amherst, MA, USA
    The Dynamic Population Modeler (DPM(+1)) employs a birth cohort framework to estimate effects on population mortality if tobacco use patterns shift from a higher- to lower-risk product. DPM(+1) allows for evaluation of changes in use patterns within the ...
  4. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 038 (also presented at CORESTA 2018)

    Comparing direct and indirect assessments of perceptions of reduced risk for a modified-risk tobacco product

    SHIFFMAN S.(1); CURTIN G.M.(2)
    (1) PinneyAssociates, Pittsburgh, PA, USA; (2) RAI Services Company, Winston-Salem, NC, USA
    Manufacturers seeking to make claims about modified-risk tobacco products (MRTPs) must assess consumers' perceptions of absolute and relative risks for that product. We cross-validate data from two methods: (a) indirect assessments based on the ...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 039 (also presented at CORESTA 2018)

    Consumers’ perceptions of disease-specific modified-risk claims are best evaluated in a disease-specific manner

    SHIFFMAN S.(1); CURTIN G.M.(2)
    (1) PinneyAssociates, Pittsburgh, PA, USA; (2) RAI Services Company, Winston-Salem, NC, USA
    Manufacturers seeking to make claims about modified-risk tobacco products (MRTPs) must assess consumers' perceptions of risk reduction for that product. Claims made for the MRTP and assessment of perceived risk reduction can be global (e.g., &quot ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 38

    Assessing the likelihood and magnitude of a population health benefit following market introduction of a modified risk tobacco product (MRTP)

    CURTIN G.(1); SULSKY S.(2); BACHAND A.(2)
    (1) RAI Services Co., Winston-Salem, NC, U.S.A.; (2) Ramboll Environ US Corp., Amherst, MA, U.S.A.
    The evaluation and implementation of tobacco policies intended to reduce harm to the population as a whole, including tobacco users and non-users, must assess the potential for both intended and unintended consequences associated with those policies. ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 39

    Addressing U.S. FDA’s population health standard for Camel Snus with modified risk messaging

    CURTIN G.(1); BACHAND A.(2); SULSKY S.(2); GERLACH K.(3); PILLITTERI J.(4); SHIFFMAN S.(3)
    (1) RAI Services Co., Winston-Salem, NC, U.S.A.; (2) Ramboll Environ US Corp., Amherst, MA, U.S.A.; (3) Pinney Associates, Inc., Pittsburgh, PA, U.S.A.; (4) Pinney Associates, Inc., Burlington, VT, U.S.A.
    R.J. Reynolds Tobacco Company has submitted Modified Risk Tobacco Product applications to the U.S. Food and Drug Administration seeking risk modification orders for Camel Snus advertising, which includes information that smokers who switch completely to ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 40

    FDA’s proposed NNN product standard: review of the scientific evidence

    MARANO K.M.(1); BACHAND A.(2); LIU C.(1); SULSKY S.(2); MARIANO G.(2); CURTIN G.M.(1); PARMS T.(1); GREEN T.(3); GENTRY P.R.(3)
    (1) RAI Services Co., Winston-Salem, NC, U.S.A.; (2) Ramboll Environ US Corp., Amherst, MA, U.S.A.; (3) Ramboll Environ, Monroe, LA, U.S.A.
    The U.S. Food and Drug Administration (FDA) has published a proposed standard of 1 µg/g (dry weight) N-nitrosonornicotine (NNN) in finished smokeless tobacco products. FDA’s rationale for the standard is that NNN is a potent carcinogen, NNN is a major ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 50 (also presented at TSRC 2017)

    Flavored e-cigarette use among U.S. adults: results from two national surveys

    SHIFFMAN S.(1,2); SEMBOWER M.(1); KIM M.(3); CURTIN G.(3)
    (1) PinneyAssociates, Inc., Pittsburgh, PA, U.S.A.; (2) University of Pittsburgh, Pittsburgh, PA, U.S.A.; (3) RAI Services Co., Winston-Salem, NC, U.S.A.
    Flavored e-cigarettes have generated much controversy and interest. To examine flavored e-cigarette use among U.S. adults, we performed analyses of two national surveys. Population Assessment of Tobacco and Health (PATH) provides a representative, ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 51 (also presented at TSRC 2017)

    Variations in intensity of e-cigarette use, smoking history, and demographics among past-30-day e-cigarette users

    SHIFFMAN S.(1,2); SEMBOWER M.(1); KIM M.(2); CURTIN G.(2)
    (1) PinneyAssociates, Inc., Pittsburgh, PA, U.S.A.; (2) University of Pittsburgh, Pittsburgh, PA, U.S.A.; (3) RAI Services Co., Winston-Salem, NC, U.S.A.
    Analyses that examine e-cigarette use often define "users" as those with any past-30-day use; this ignores substantial variations in use patterns, and leads to incorrect perceptions of e-cigarette users. We used data from a national sample of ...