1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 33

    Quantitative risk assessment (QRA) indicates reduced risk potential for carcinogenic and non-carcinogenic effects of the aerosol of the next generation products (NGPs) compared to reference cigarettes

    AYALA-FIERRO F.(1); CZEKALA L.(2); SIMMS L.(2); RUDD K.(2); CAVA G.(2); STEVENSON M.(2)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) Imperial Brands PLC, Bristol, U.K.
    In order to understand the potential relative health risks of NGPs compared to cigarettes, we compared the relative risks of aerosols from tobacco-containing and tobacco-free NGPs to the smoke generated from a reference cigarette. Quantitative Risk...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 19

    Human mouth-level transfer rate of menthol, 1.8-cineole and nicotine from Swedish pouched snus

    TROUDE V.(1); GADOIS-POMMEREUL S.(1); CLARKE A.(2); SIMMS L.(2)
    (1) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France; (2) Imperial Tobacco Limited, Bristol, U.K.
    To facilitate the development of a transfer model which can be used to estimate human exposure to flavour and tobacco constituents, a human in vivo study involving 198 Swedish active snus users was conducted. All subjects agreed to participate in the...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, STPOST 03

    Analytical method to model human mouth-level transfer of ingredients from Swedish pouched snus

    GRAPTON S. (1); GADOIS-POMMEREUL S.(1); TROUDE V.(1); BLANCHET M. (1); CLARKE A.(2); SIMMS L.(2)
    (1) SEITA, Imperial Tobacco Group, Fleury-les-Aubrais, France; (2) Imperial Tobacco Limited, Bristol, U.K.
    In parallel with the human study[1] a laboratory in vitro assay was conducted with three media: artificial saliva, water and 1% ß-cyclodextrin in water, using two snus products that were indistinguishable apart from the flavour application rate. To...