CORESTA Congress, New Orleans, 2002, STPOST 05
Changes in free levels of oxidative DNA damage/repair products in the alveolar fluid of smokers after switching to Eclipse, a cigarette that primarily heats rather than burns tobacco
R.J. Reynolds Tobacco Company, Winston Salem, NC, USA
Oxidative DNA damage has been implicated in aging, carcinogenesis, heart disease, and neurodegenerative diseases. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a principal stable marker of hydroxyl radical damage to DNA. Tobacco smoking has been shown to...