1. CORESTA Meeting, Agronomy/Phytopathology, 2021, Online, AP 49

    Consequences of molecular genetic alteration of leaf nitrate levels on TSNAs, alkaloids, flowering time, and biomass in Burley tobaccos

    DEWEY R.E.(1); BOVET L.(2); GOEPFERT S.(2); CAMPANONI P.(2); LEWIS R.S.(1)
    (1) North Carolina State University, Dept. of Crop and Soil Sciences, Raleigh, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchatel, Switzerland
    We have previously demonstrated that tobacco-specific nitrosamine (TSNA) levels in Burley tobaccos can be substantially lowered using two distinct molecular genetic techniques designed to impede the plant’s ability to store high levels of free...
  2. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 24

    Downregulation of a putative nitrate transporter gene substantially reduces the accumulation of TSNAs in air-cured tobaccos

    GOEPFERT S.(1); BOVET L.(1); LU J.(2); CAMPANONI P.(1); LEWIS R.S.(2); DEWEY R.E.(2)
    (1) Philip Morris Products S.A. (part of Philip Morris International group of companies), PMI R&D, Neuchâtel, Switzerland; (2) North Carolina State University, Department of Crop Science, Raleigh, NC, U.S.A.
    Air-cured Burley tobacco leaves typically exhibit high levels of nicotine-derived nitrosamine ketone (NNK) and N'-nitrosonornicotine (NNN). It has been previously demonstrated that leaf nitrate accumulation in air-cured tobaccos serves as the source...