TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 82
Assessment of two high throughput in vitro methods for the quantification of cigarette smoke induced micronuclei
(1) ITG Brands, Greensboro, NC USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
Micronuclei (MN) formation, in vitro and in vivo, is a DNA damage endpoint utilized to determine the genotoxicity potential of individual compounds or complex mixtures. Historically, MN data collection relied on a manual scoring process; however,...