1. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 82

    Assessment of two high throughput in vitro methods for the quantification of cigarette smoke induced micronuclei

    COOPER B.(1); MISRA M.(1); LEVERETTE R.(2)
    (1) ITG Brands, Greensboro, NC USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    Micronuclei (MN) formation, in vitro and in vivo, is a DNA damage endpoint utilized to determine the genotoxicity potential of individual compounds or complex mixtures. Historically, MN data collection relied on a manual scoring process; however, advances ...
  2. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 83

    In vitro toxicity screening of blu electronic cigarette liquids and implications for human exposure

    MISRA M.(1); LEVERETTE R.(2); COOPER B.(1); BENNETT M.B.(1)
    (1) ITG Brands, Greensboro, NC USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The popularity and sales of electronic cigarettes (e-cigs) have increased significantly with thousands of available flavors, many with limited knowledge regarding their toxicity. An initial in vitro toxicological screening was conducted for several ...