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128 results

  1. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 048

    Survey of nicotine, NNK, NNN, pH and physical properties of little cigars in the US market place

    LIU Youbang(1); HASSINK M.D.(1); TAYLOR K.M.(1); WATSON C.(2); CHAFIN D.(2); LAWLER T.(2); VALENTIN-BLASINI L.(2); KIMBRALL B.(2)
    (1) U.S. Food and Drug Administration, Silver Spring, MD, USA; (2) Centers for Disease Control and Prevention, Atlanta, GA, USA
    In May 2016, the jurisdiction of the Federal Food Drug and Cosmetic Act was extended to include all tobacco products, including cigars. Because limited information exists on the chemistry of cigar filler and smoke, 60 brands of popular little cigars sold ...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 098

    CTP submissions – tips and insight for preparing an electronic submission

    SHOLTES D.(1); SMITH J.K.(1); ANGERMEIER G.(2)
    (1) U.S. Food & Drug Administration, Silver Spring, MD, USA; (2) WiseDesign, McLean, VA, USA
    Currently, tobacco product submissions are organized differently across application types and often, across applicants, and are received in a format that is not amenable for reviewers to organize and easily find what they need. This “unstructured” format ...
  3. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 078

    Development of a multi-stage liquid extraction method for the quantitative analysis of flavors in tobacco filler

    MATHIS J.A.; STANELLE R.A.; DIMANDIA J.-M.D.
    U.S. Food and Drug Administration, Atlanta, GA, USA
    A method to quantify flavor chemicals in the filler of combustible tobacco products was validated using GC-MS. The tobacco filler samples from cigarettes, little cigars, cigarillos, and cigars were prepared in a multi-step extraction procedure using ethyl ...
  4. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, AP 54

    The regulation of autophagy of susceptible Nicotiana tabacum under tobacco mosaic virus infection

    YANG Jinguang(1); LIU Xaingfu(1); LIU Wei(1); QIAN Yumei(1); ZHANG Jing(2); LI Wei(2); DONG Shifei(2); WANG Yaofeng(3); HUANG Mingdi(4); WANG Fenglong(1)
    (1) Tobacco Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Tobacco Pest Monitoring Controlling & Integrated Management, Qingdao, P.R. China; (2) Hongyun Honghe Tobacco (Group) Co., Ltd., Kunming, P.R. China; (3) Qingyang Branch of Gansu Province Tobacco Company, Xifeng, P.R. China; (4) Longnan Tobacco Company, Gansu Tobacco Cooperation, Wudu 746000, P.R. China
    Autophagy (or self-eating) is an important conserved process by which eukaryotic cells recycle intracellular components. This study was undertaken to elucidate whether tobacco mosaic virus (TMV) infection on tobacco plants induced autophagy. TMV-U1 and ...
  5. CORESTA Congress, Berlin, 2016, Agronomy/Phytopathology Groups, APPOST 26

    Crop compliance: crop protection agents testing programme within purchases

    BODE L.M.; EVANS W.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    In order to ensure the compliance of our products, leaf grade purchases are monitored for the presence of any residual crop protection agents (CPA). CPA residue levels are first assessed for compliance against limits set by regulatory authorities and ...
  6. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 04

    Impact of different vaping machines on metal contaminations of e-cigarette aerosols

    OTTE S.; NOWAK S.; INTORP M.
    Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany
    The presence of trace metals in e-liquids or aerosol of electronic cigarettes (e-cigarette) has been previously reported [1]. It has also been demonstrated that contamination with tin, aluminum, copper, iron and nickel may occur from certain parts of a ...
  7. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 26

    A review of aerosol exposure systems relative to the analysis of cytotoxicity: a CORESTA In vitro Toxicity Testing Sub-Group perspective

    THORNE D.(1); WIECZOREK R.(2); FUKUSHIMA T.(3); SHIN H.J.(4); LEVERETTE R.(5); BALLANTYNE M.(6); LI X.(7); BOMBICK B.(5)
    (1) British American Tobacco, R&D Centre, Southampton, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) Japan Tobacco Inc., Scientific Product Assessment Centre, Yokohama, Kanagawa, Japan; (4) KT&G Corporation, Daejeon, South Korea; (5) RAI Services Company, Winston-Salem, NC, U.S.A.; (6) Covance Laboratories Ltd, Harrogate, U.K.; (7) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China
    Aerosol exposure systems offer researchers a variety of ways to customise the exposure set-up, modify experimental parameters and provide a novel and versatile platform for in vitro aerosol research. These systems produce an aerosol that more closely ...
  8. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 32

    Cellular transformation activity of different tobacco condensates in the Bhas 42 cell assay

    STEVENSON M.(1); WIECZOREK R.(2); SIMMS L.(1); PANT K.(3)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (3) BioReliance, Sigma-Aldrich Corp., Rockville, MD, U.S.A.
    Carcinogenesis has been described as a multi-stage process comprising of initiation, promotion and progression. Smoking is a cause of serious disease in smokers, including lung cancer. Determining the carcinogenic potential of a tobacco product ingredient ...