Search Results

352 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 14

    Field tests of loss-of-function tobacco lines of eIF(iso)4E for resistance to tobacco bushy top disease and agronomic traits

    KOGA K.(1); SHINJO A.(1); MAINJENI C.E.D.(2); MSANGOSOKO K.R.(2); UDAGAWA H.(1); TAKAKURA Y.(1)
    (1) Japan Tobacco Inc., Leaf Tobacco Research Center, Oyama, Tochigi, Japan; (2) Agricultural Research and Extension Trust, Department of Research and Technical Services, Lilongwe, Malawi
    Tobacco bushy top disease (TBTD) is one of the serious diseases affecting tobacco (Nicotiana tabacum L.) production in African countries such as Malawi, Zambia, Tanzania and Ethiopia. This disease is caused by a mixed infection of tobacco bushy top...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 05

    Influence of disease resistance on the yield and quality in Burley tobacco

    NAKAMURA T.; TAKEMATSU T.; IWAI Y.
    Japan Tobacco Inc., Leaf Tobacco Research Center, Oyama, Tochigi, Japan
    Tobacco breeders recognise empirically that introduction of certain disease resistance is accompanied by negative effects on agronomic traits such as decrease in yield and quality. Only a few studies have quantitatively clarified the negative effects...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 18

    Human precision-cut lung slices as a screening tool: increased throughput, cryopreservation, and detection of DNA adducts for next generation tobacco product evaluation

    BEHRSING H.P.(1); DESAI P.(1); AMIN K.(2); BALBO S.(3); HECHT S.S.(2); SHEEHAN D.(1); CASTRO N.(1); ALLEN D.(4)
    (1) Institute for In Vitro Sciences, Inc., Gaithersburg, MD, U.S.A.; (2) University of Minnesota, Division of Environmental Health Sciences, Minneapolis, MN, U.S.A.; (3) University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, U.S.A.; (4) Integrated Laboratory Systems, Inc., Morrisville, NC, U.S.A.
    Human-relevant, in vitro/ex vivo assays are considered an ethical and economically viable manner by which to screen the many chemicals requiring hazard assessment, such as next generation tobacco product (NGTP) ingredients. Human precision-cut lung...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 11 (also presented at TSRC 2019)

    Simultaneous determination analysis of glycerol, propylene glycol, nicotine, menthol and water by discharge ionisation detector on gas chromatography

    SHIMAZU A.; OMORI F.
    Japan Tobacco Inc., Product Quality Research Center, Tokyo, Japan
    CORESTA developed a recommended method (CRM 84) for determination of Glycerin (G), Propylene Glycol (PG), nicotine and water in the aerosol of e-cigarettes by gas chromatography (GC) with flame ionisation detector (FID) and thermal conductivity...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 36

    Use of ex vivo precision-cut lung slices as a screening tool for potential respiratory toxicity of e-liquids

    BEHRSING H.P.(1); SHEEHAN D.(1); AMIN K.(2); LEE K.M.(3); OLDHAM M.(4); RAABE H.(1)
    (1) Institute for In Vitro Sciences, Inc., Gaithersburg, MD, U.S.A.; (2) University of Minnesota, Minneapolis, MN, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) former Altria Client Services employee
    The Family Smoking Prevention and Tobacco Control Act gave the FDA regulatory authority over next generation tobacco products (NGTP) such as e-vapor products. E-vapor product liquids contain a variety of ingredient combinations that should be...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 39

    Risk assessment of a novel tobacco vapour product using ToxTracker® assay and high content screening in vitro

    MUNAKATA S.; ERAMI K.; HASHIZUME T.
    Japan Tobacco Inc., R&D Group, Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    A novel tobacco vapour product (NTV) showed its lower genotoxic and cytotoxic potentials in the in vitro bacterial reverse mutation assay, micronucleus assay, and neutral red uptake assay compared with a combustible tobacco product. This study aimed...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 47

    Identification, discussion and recommendations for the optimal generation and use of in vitro genotoxicity assay data for tobacco and nicotine products

    DESAI P.(1); CURREN R.(1); MOORE M.M.(2)
    (1) Institute for In Vitro Sciences, Gaithersburg, MD, U.S.A.; (2) Ramboll Environ Inc., Little Rock, AR, U.S.A.
    The Institute for In Vitro Sciences is sponsoring a series of workshops to identify, discuss and develop recommendations for optimal scientific/technical approaches for utilizing in vitro regulatory genotoxicity assay data within and across tobacco...