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3 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 37

    Good relationship between saliva cotinine kinetics and plasma cotinine kinetics after smoking one cigarette

    YUKI D.; KIKUCHI A.; MIURA N.; KAKEHI A.; ONOZAWA M.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    This study investigated the relationship between plasma and saliva cotinine kinetics after smoking one cigarette and the relationship between cotinine kinetics and estimated nicotine intake, which was calculated as mouth level exposure (MLE) of nicotine, ...
  2. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 18

    Estimation of mouth level smoke exposure in cigarettes with different tar content using filter analysis

    BITO R.; MINAMI N.; KAKEHI A.; YUKI D.; ONOZAWA M.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    Filter analysis for evaluating the mouth level exposure (MLE) of smokers is non-invasive, allowing ordinary smoking behaviour with simple sample collection. We investigated 1) estimated MLEs to 36 smoke constituents using filter analysis, 2) MLEs of ...
  3. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 02

    Report on biological researches using a heated cigarette. Part 2: Clinical exposure study

    SAKAGUCHI C.; KAKEHI A.; MINAMI N.; KIKUCHI A.; ONOZAWA M.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    The objective of this clinical study was to investigate changes in levels of biomarkers of cigarette smoke exposure (BoExp) in healthy adult male smokers who switched to heated cigarettes (HC). This was a controlled, randomised, open-label, residential ...