TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 11
An inter-laboratory comparison of urinary 3-hydroxypropylmercapturic acid measurement demonstrates good reproducibility between laboratories.
(1) British American Tobacco, Group R&D, Southampton, UK; (2) ABF GmbH; (3) Celerion; (4) Labstat International Inc.; (5). Covance Laboratories Ltd.
Background- Biomarkers have been used extensively in clinical studies to assess toxicant exposure in smokers and non-smokers and have recently been used in the evaluation of novel tobacco products. The urinary metabolite 3-HPMA, a metabolite of the major ...