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  1. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 07

    Complete artificial saliva alters expression of proinflamma-tory cytokines in human dermal fibroblasts

    MALPASS G.E.(1); ARIMILLI S.(1); PRASAD G.L.(2); HOWLETT A.C.(1)
    (1) Wake Forest University Health Sciences, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Complete artificial saliva (CAS) is a saliva substitute often used as a vehicle for test articles, including, smokeless tobacco. We discovered, using polymerase chain reaction gene expression array analyses, that CAS increased gene expression for certain ...
  2. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 08

    Method development for enumeration of endothelial progenitor cells (EPCs)

    PRASAD G.L.(1); ARIMILLI S.(2); JONES B.A.(1); FEARON I.(3)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) Wake Forest University Baptist Health, Winston-Salem, NC, USA; (3) British American Tobacco GR&D, Southampton, UK
    Endothelial progenitor cells (EPCs) are a type of white blood cells present in circulation at low numbers and are hypothesized to play a role in the protection and repair of the of cardiovascular system. EPCs, characterized as cells expressing the surface ...