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156 results

  1. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 36

    Mutations of phytochelatin synthase (PCS) genes by CRISPR/Cas9 reduce accumulation of cadmium in tobacco leaves

    SEO H.S.; LEE Y.G.; KIM K.C.; OH K.H.; JEON E.Y.; NA W.H.; LEE J.H.
    KT&G Research Institute, Daejeon, South Korea
    Cadmium (Cd) is classified as a Class 1 “known human carcinogen” by the International Agency for Research on Cancer (IARC). Cd accumulation in crop plants including tobacco (Nicotiana tabacum) can lead to human exposure. Cd is a non-essential heavy...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 08

    Effects of smoking parameters on aerosol delivery of next generation of Heated Tobacco Products (HTPs)

    JIN S.J.; LIM G.H.; SHIN G.W.; SHIN S.H.; LEE J.M.
    KT&G Research Institute, Daejeon, South Korea
    In recent years there have been many changes in the cigarette market. Cigarette users are accepting novel products along with conventional cigarettes. These novel products are sometimes referred to as next generation products (NGPs), and include...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 17

    Comparison of in vitro toxicity of heated tobacco products and combustible cigarettes

    KT&G Research Institute, Daejeon, South Korea
    In recent years, the paradigm of the tobacco industry has been changing with the development of heated tobacco products (HTPs) that have a similar taste to cigarettes but significantly reduce the amount of smoke components. The purpose of this study...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 22

    Study of combustion patterns for ignition propensity test using several kinds of substrates and cigarettes

    LEE D.H.; KIM Y.S.; SHIN H.J.; LEE M.Y.
    KT&G Research Institute, Daejeon, South Korea
    The ignition propensity of cigarettes can be measured in accordance with ISO 12863:2010. It recommends the use of Whatman No. 2 filter paper as a substrate. Actually most laboratories use this filter paper and there may be a need to replace Whatman...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 58

    A consortium approach for consumer-reported outcome measures to assess tobacco- and nicotine-containing products

    ACQUADRO C.(1) on behalf of the CORESTA CROM Task Force: AYALA-FIERRO F.(2); BLACK R.(3); CAHOURS X.(4); CHREA C.(5); CURTIN G.(6); GILES L.(7); McCAFFREY S.(3); PARK C.H.(8); PRASAD K.(9); SHERWOOD N.(10); SHIFFMAN S.(11); SMITH J.(6); SPIES E.(5)
    (1) Mapi Research Trust, Lyon, France; (2) ITG Brands, Greensboro, NC, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) SEITA - Imperial Brands, Paris, France; (5) Philip Morris Products S.A., Neûchatel, Switzerland; (6) RAIS, Winston-Salem, NC, U.S.A.; (7) JT Int'l SA, Genève, Switzerland; (8) KT&G Research Institute, Daejeon, Republic of Korea; (9) British American Tobacco, Southampton, U.K.; (10) Neil Sherwood Consulting, Commugny, Switzerland; (11) Pinney Associates, Pittsburgh, PA, U.S.A.
    In the tobacco space, consumer-reported outcome measures (CROM) are essential for understanding motivations, subjective effects, and behavior. Such measures have become particularly important with the advent of candidate modified risk tobacco...
  6. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 11

    Breeding of an extremely low nicotine Burley tobacco line and its characteristics

    NA Woong-Hyun; KIM Kwang-Chul; OH Kyung-Hwan; JEON Eun-Young; LEE Jeong-Heon
    KT&G R&D Headquarters, Daejeon, South Korea
    Worldwide, regulation on tobacco and cigarettes is increasing more and more. In addition, the U.S. Food and Drug Administration (FDA) has recently announced a plan for regulation of nicotine content in tobacco. In this situation, not only flue-cured...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 02

    Effect of heating temperature on chemical characterisation and biological activity of tobacco smoke emission

    SHIN Han-Jae; GWAK Hyo-Min; LEE Moon-Yong
    KT&G Research Institute, Daejeon, South Korea
    Cigarette smoke is mainly produced by distillation, pyrolysis and combustion reactions when the tobacco is burnt. Heating type cigarettes have been reported to have the potential to reduce or eliminate some toxicants found in cigarette smoke because...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 11

    Determination of the transfer of nicotine and selected ingredients into heat-not-burn tobacco product mainstream aerosol by using gas chromatography

    YUN J.H.; JIN S.J.; LIM G.H.; LEE J.M.
    KT&G Research Institute, Daejeon, South Korea
    Recently, tobacco manufacturing companies launched heat-not-burn tobacco products (HNBs) such as iQOS, Glo and lil. The aerosol of HNBs is generated by the heating of a tobacco type material below 350 °C. In conventional cigarettes the aerosol is...
  9. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 62

    Immune functions are perturbed to a greater extent with smoking rather than moist snuff use

    TRAN Q.T.(1); ARIMILLI S.(2); JOHNSON E.(3); LIU Gang(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Wake Forest University, School of Medicine, Department of Microbiology and Immunology, Winston-Salem, NC, U.S.A.; (3) University of North Carolina, Department of Mathematics and Statistics, Greensboro, NC, U.S.A.
    Cigarette smoking is a major risk factor for lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease (CVD). Existing epidemiological data suggest moist snuff consumption is generally associated with reduced health risks...
  10. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 066

    Distinct gene expression changes in peripheral blood mononuclear cells exposed to combustible versus non-combustible tobacco product preparations

    (1) RAI Services, Winston-Salem, NC, USA; (2) Wake Forest University, Winston-Salem, NC, USA; (3) Quire Inc., Memphis, TN, USA
    Cigarette smoking exerts diverse physiological effects including immune suppression. Existing epidemiological data show that consumption of smokeless tobacco products, such as moist snuff, is less harmful relative to smoking. We previously...