1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 62

    Immune functions are perturbed to a greater extent with smoking rather than moist snuff use

    TRAN Q.T.(1); ARIMILLI S.(2); JOHNSON E.(3); LIU Gang(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, U.S.A.; (2) Wake Forest University, School of Medicine, Department of Microbiology and Immunology, Winston-Salem, NC, U.S.A.; (3) University of North Carolina, Department of Mathematics and Statistics, Greensboro, NC, U.S.A.
    Cigarette smoking is a major risk factor for lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease (CVD). Existing epidemiological data suggest moist snuff consumption is generally associated with reduced health risks...
  2. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 080

    Differential gene expression and functional responses in peripheral blood mononuclear cells pretreated with combustible and non-combustible tobacco products

    TRAN Q.T.(1); ARIMILLI S.(2); LIU Gang(1); MAKENA P.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Wake Forest School of Medicine, Winston-Salem, NC, USA
    Chronic smoking is known to alter immune responses, which compromises tumor surveillance and host defense against microbial infections. We previously showed that smokers (SMK) exhibit distinct peripheral blood mononuclear cell (PBMC) gene expression...