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49 results

  1. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 090

    Differential regulation of ion channel function from exposures to cigarette smoke and ENDs preparations

    RAYNER R.E.(1); MAKENA P.(2); PRASAD G.L.(2); CORMET-BOYAKA E.(1)
    (1) The Ohio State University, Columbus, OH, USA; (2) RAI Services Company, Winston Salem, NC, USA
    Cigarette smoking is known to disrupt the normal mucociliary function of the lungs, whereas the effect of Electronic Nicotine Delivery Systems (ENDS) is incompletely understood. This study aimed to compare the effects of acute exposure of primary...
  2. CORESTA Congress, Sapporo, 2012, Plenary Session, Invited Paper 2

    Molecular mechanisms of smoking induced cardiovascular disease: insights from cellular and animal models

    ZWEIER J.L.
    Davis Heart & Lung Research Institute and the John H. and Mildred C. Lumley Chair in Medicine at the Ohio State University College of Medicine, USA
    This lecture will review how smoking contributes to cause cardiovascular disease and the critical role of endothelial dysfunction in this process. The process by which the critical endothelial-derived relaxing factor, nitric oxide (NO), and...
  3. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 11

    Application of carbon fiber microelectrodes for measurement of kinetic constants of nitric oxide decay in blood

    ZWEIER J.L.; XIAOPING LIU; EL-SHERBINY G.A.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Endogenous nitric oxide (NO) is a potent vasodilator that regulates vascular tone. There is evidence that cigarette smoking increases superoxide production in blood vessels by rapidly inactivating NO. This impaired NO bioavailability is a critical...
  4. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 39

    Identification of differentially expressed proteins in blood plasma of control and cigarette smoke-exposed mice by 2-d differential in-gel electrophoresis/mass spectrometry

    ZWEIER T.L.; TEWARI A.K.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Cigarette smoke exposure is known to induce chronic obstructive pulmonary disease, atherosclerosis, and several types of cancer in humans and also in animal models. Smoking leads to oxidative stress and inflammation that are important in triggering...
  5. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 51

    Chronic cigarette smoke exposure induces vascular dysfunction through upregulation of cytoglobin in mouse aorta

    EL-MAHDY M.A.; EL-SHERBINY G.A.; ABDELGHANY T.M.; ZWEIER J.L.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Inst., Columbus, OH, USA
    Cigarette smoking is a risk factor for cardiovascular disease. The relationship between smoking and cardiovascular disease results from multiple mechanisms that interact to contribute to several pathological conditions, including vascular...
  6. TSRC, Tob. Sci. Res. Conf., 2010, 64, abstr. 52

    Chronic cigarette smoke exposure impairs vascular endothelial function through a tetrahydrobiopterin-dependent mechanism

    ABDELGHANY T.M.; EL-SHERBINY G.A.; EL-MAHDY M.A.; ZWEIER J.L.
    Ohio State University, Center for Environmental and Smoking Induced Diseases, Davis Heart and Lung Research Institute, Columbus, OH, USA
    Cigarette smoke exposure (CSE) is one of the major risk factors of cardiovascular disease. Although tobacco smoking is associated with the onset of atherosclerosis, coronary disease, and ischemic heart disease, the precise mechanism by which these...
  7. CORESTA Congress, Kyoto, 2004, A 02

    Decision support system for soil fertility and water quality - evaluation in FCV tobacco- growing zones of India

    KRISHNAMURTHY V.; RAVISANKAR H.; DEO SINGH K.
    Central Tobacco Research Institute (CTRI), Rajahmundry (A.P.) India
    Information Technology has become an integral part of our day-to-day life. In agriculture, computers are extensively used to disseminate the information on soils, water, climatic conditions, pest and disease management and one such information system...