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47 results

  1. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 057

    AKR1C1 as a biomarker for differentiating the biological effects of combustible from non-combustible tobacco products

    TRAN Q.T.(1); WOO S.(2); HENDERSON D.(2); GAO H.(3); ZACHARIAS W.(3); LIU G.(1); PRASAD G.L.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Axio Research, Seattle, WA, USA; (3) University of Louisville School of Medicine, Louisville, KY, USA
    Smoking has been established as a major risk factor for developing oral squamous cell carcinoma (OSCC), but less attention has been paid to the effects of smokeless tobacco products. Our objective is to identify potential biomarkers to distinguish...
  2. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 06

    Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells

    ZACHARIAS W.(1); GAO H.(1); PRASAD G.L.(2)
    (1) Dept. of Medicine, J.G. Brown Cancer Center, University of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA
    We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
  3. TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 30

    Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells

    ZACHARIAS W.(1); HONG GAO(1); PRASAD G.L.(2)
    (1) Brown Cancer Center, Univ. of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
  4. TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 30

    Microarray-based gene expression profiles of oral cavity cells exposed to different tobacco preparations.

    ZACHARIAS W.(1); HONG G.(1); PRASAD G.L.(2)
    (1) Dept. of Medicine, J.G. BROWN Cancer Center, Univ. of Louisville, Louisville, KY; (2) RJ Reynolds Tobacco Co., Winston-Salem, NC, USA
    Global gene expression profiles were determined for a panel of oral cavity cells in response to treatment by different tobacco preparations. Two human oral squamous cell carcinoma cell lines (101A, 101B) and normal gingival epithelial cells (HGEC)...
  5. CORESTA Congress, Kyoto, 2004, A 02

    Decision support system for soil fertility and water quality - evaluation in FCV tobacco- growing zones of India

    KRISHNAMURTHY V.; RAVISANKAR H.; DEO SINGH K.
    Central Tobacco Research Institute (CTRI), Rajahmundry (A.P.) India
    Information Technology has become an integral part of our day-to-day life. In agriculture, computers are extensively used to disseminate the information on soils, water, climatic conditions, pest and disease management and one such information system...
  6. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 140, PPOST8

    Bio-intensive integrated management of budworm, Helicoverpa armigera in FCV tobacco

    SITARAMAIAH S.; GUNNESWARA RAO S.; RAMAPRASAD G.; SREEDHAR U.
    Central Tobacco Research Institute (CTRI), Rajahmundry (A.P.) India
    Tobacco budworm, Helicoverpa armigera , is one of the limiting factors in successful production of Flue Cured Virginia (FCV) tobacco in Andhra Pradesh, India. It infests the crop during the grand growth period and inflicts severe damage to the bud...
  7. Bull. Spec. CORESTA Congress, Lisbon, 2000, p. 97, A9

    Lowering the nicotine content of flue-cured tobacco cultivars in South Africa

    VAN TONDER C.S.M.; KRUGER J.; DIPPENAAR M.C.
    Tobacco and Cotton Research Institute, Soil and Crop Science Division, Rustenburg, South Africa
    The nicotine content of flue-cured tobacco produced in the RSA is determined by factors suchas soil fertility, climatic conditions and production practices. The nicotine content of the leaf cannot be reduced dramatically without a detrimental effect...