CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 27
Interaction of nicotine, NAT and NAB with NNK and NNN induced by cytochrome P450 2A13 in aqueous solution
Beijing Cigarette Factory, Shanghai Tobacco Group Corporation, Ltd., CNTC, Beijing, P.R. China
NNK and NNN are considered to be the most carcinogenic of the four TSNAs. However, these TSNAs are carcinogenic to humans only after being metabolically activated by cytochrome P450 enzyme. There are other weak carcinogens, such as NAT and NAB, and...