CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, ST 48
The proposed use of human cells to cover the ‘R’ end point for EUTPD2 data requirements from a 21st century toxicology perspective
(1) Imperial Tobacco Limited, Bristol, U.K.; (2) Stemina, Madison, WI, U.S.A.
In 2007 the National Academies of Sciences released “Toxicity Testing in the 21st Century: A Vision and a Strategy”, a new toxicological paradigm, moving away from the idea of high dose animal tests as the ‘gold standard’ and focusing on the use of...